Pathophysiology of Down's syndrome and rare dose-effect diseases causing intellectual disabilities (ID) or autism spectrum disorders (ASD) and other comorbidities
Team Leader : Yann HERAULT
Department : Translational medecine and neurogenetics
Yann HERAULT
Researcher
yann.herault@igbmc.fr
Research team(s)
Research subgroup(s)
Publications
2017
Article in a journal
Atp6ap2 ablation in adult mice impairs viability through multiple organ deficiencies
- Olivia Wendling
- Marie-France Champy Methlin
- Solène Jaubert
- Guillaume Pavlovic
- Aline Dubos
- Loic Lindner
- Hugues Jacobs
- Manuel Mark
- Roy Combe
- Isabelle Goncalves da Cruz
- Hervé Luche
- John Mudgett
- Thomas Rosahl
- Tania Sorg-Guss
- Marie Malissen
- Patrick Reilly
- Yann Herault
Scientific Reports ; Volume: 7
Article in a journal
A Fast, Easy, and Customizable Eight-Color Flow Cytometric Method for Analysis of the Cellular Content of Bronchoalveolar Lavage Fluid in the Mouse
- Francois Daubeuf
- Julien Becker
- Juan Aguilar-Pimentel
- Claudine Ebel
- Martin Hrabě de Angelis
- Yann Herault
- Nelly Frossard
Current Protocols in Mouse Biology ; Volume: 7 ; Page: 88-99
Article in a journal
Efficient and rapid generation of large genomic variants in rats and mice using CRISMERE
- Marie-Christine Birling
- Laurence Schaeffer
- Philippe Andre
- Loic Lindner
- Damien Marechal
- Abdelkader Ayadi
- Tania Sorg-Guss
- Guillaume Pavlovic
- Yann Herault
Scientific Reports ; Volume: 7
Article in a journal
Introduction to Mammalian Genome Special Issue: Genome Editing
- Lydia Teboul
- Yann Herault
- Cynthia Smith
- Bruce Whitelaw
Mammalian Genome ; Volume: 28 ; Page: 235-236
Article in a journal
Modeling human disease in rodents by CRISPR/Cas9 genome editing
- Marie-Christine Birling
- Yann Herault
- Guillaume Pavlovic
Mammalian Genome ; Volume: 28 ; Page: 291-301
Article in a journal
Mouse models of 17q21.31 microdeletion and microduplication syndromes highlight the importance of Kansl1 for cognition
- Thomas Arbogast
- G Iacono
- C Chevalier
- N Afinowi
- X Houbaert
- M van Eede
- C Laliberte
- Marie-Christine Birling
- K Linda
- H Meziane
- M Selloum
- T Sorg
- N Nadif Kasri
- D Koolen
- H Stunnenberg
- R Henkelman
- M Kopanitsa
- Yann Humeau
- B de Vries
- Yann Herault
PLoS Genetics ; Volume: 13
Article in a journal
Disease model discovery from 3,328 gene knockouts by The International Mouse Phenotyping Consortium
- Terrence Meehan
- Nathalie Conte
- David West
- Julius Jacobsen
- Jeremy Mason
- Jonathan Warren
- Chao Chen
- Ilinca Tudose
- Mike Relac
- Peter Matthews
- Natasha Karp
- Luis Santos
- Tanja Fiegel
- Natalie Ring
- Henrik Westerberg
- Simon Greenaway
- Duncan Sneddon
- Hugh Morgan
- Gemma Codner
- Michelle Stewart
- ...
Nature Genetics ; Volume: 49 ; Page: 1231-1238
2016
Article in a journal
Physiological Expression of AMPKγ2 Mutation Causes Wolff-Parkinson-White Syndrome and Induces Kidney Injury in Mice
- Xiaodong Yang
- John Mudgett
- Ghina Bou About
- Marie-France Champy Methlin
- Hugues Jacobs
- Laurent Monassier
- Guillaume Pavlovic
- Tania Sorg-Guss
- Yann Hérault
- Benoît Petit-Demoulière
- Ku Lu
- Wen Feng
- Hongwu Wang
- Li-Jun Ma
- Roger Askew
- Mark D. Erion
- David E. Kelley
- Robert W. Myers
- Cai Li
- Hong-Ping Guan
Journal of Biological Chemistry ; Volume: 291 ; Page: 23428-23439
Article in a journal
Fasudil treatment in adult reverses behavioural changes and brain ventricular enlargement in Oligophrenin-1 mouse model of intellectual disability
- Hamid Meziane
- Malik Khelfaoui
- Noemi Morello
- Bassem Hiba
- Eleonora Calcagno
- Sophie Reibel-Foisset
- Mohammed Selloum
- Jamel Chelly
- Yann Humeau
- Fabrice Riet
- Ginevra Zanni
- Yann Hérault
- Thierry Bienvenu
- Maurizio Giustetto
- Pierre Billuart
Human Molecular Genetics ; Volume: 25 ; Page: 2314-2323
Article in a journal
E4F1-mediated control of pyruvate dehydrogenase activity is essential for skin homeostasis
- Perrine Goguet-Rubio
- Berfin Seyran
- Laurie Gayte
- Florence F. Bernex
- Anne Sutter
- Hélène Delpech
- Laetitia Karine Linares
- Romain Riscal
- Cendrine Repond
- Genevieve Rodier
- Olivier Kirsh
- Jawida Touhami
- Jean Noel
- Charles Vincent
- Nelly Pirot
- G Pavlovic
- Yann Hérault
- Marc Sitbon
- Luc Pellerin
- Claude Sardet
- ...
Proceedings of the National Academy of Sciences of the United States of America ; Volume: 113 ; Page: 11004-11009