Molecular mechanisms of chromatin reorganization

Publications

• 2016

  • Article in a journal

    Large-Scale Overproduction and Purification of Recombinant Histone Deacetylase 8 (HDAC8) from the Human-Pathogenic Flatworm Schistosoma mansoni

    • Martin Marek
    • Tajith Baba Shaik
    • Sylvie Duclaud
    • R. J. Pierce
    • Christophe Romier

    Methods in Molecular Biology ; Volume: 1436 ; Page: 109-18

    HALDOI

• 2015

  • Chapter of the book

    Characterization and Production of Protein Complexes by Co-expression in Escherichia coli

    • Matthias Haffke
    • Martin Marek
    • Martin Pelosse
    • Marie-Laure Diebold
    • Uwe Schlattner
    • Imre Berger
    • Christophe Romier

    Structural Proteomics ; Volume: 1261 ; Page: 63-89

    HALDOI

  • Article in a journal

    Fluorescence-Based Screening Assays for the NAD+-Dependent Histone Deacetylase smSirt2 from Schistosoma mansoni

    • Matthias Schiedel
    • Martin Marek
    • Julien Lancelot
    • Berin Karaman
    • Ingrid Almlöf
    • Johan Schultz
    • Wolfgang Sippl
    • Raymond J. Pierce
    • Christophe Romier
    • Manfred Jung

    Journal of Biomolecular Screening ; Volume: 20 ; Page: 112-121

    HALDOI

  • Article in a journal  » Review article

    Schistosome sirtuins as drug targets

    • Julien Lancelot
    • Alejandro Cabezas Cruz
    • Stéphanie Caby
    • Martin Marek
    • Johan Schultz
    • Christophe Romier
    • Wolfgang Sippl
    • Manfred Jung
    • Raymond J Pierce

    Future Medicinal Chemistry ; Volume: 7 ; Page: 765-782

    HALDOI

  • Article in a journal

    Homology modeling of parasite histone deacetylases to guide the structure-based design of selective inhibitors

    • Jelena Melesina
    • Dina Robaa
    • Raymond J. Pierce
    • Christophe Romier
    • Wolfgang Sippl

    Journal of Molecular Graphics and Modelling ; Volume: 62 ; Page: 342--361

    HALDOI

  • Article in a journal  » Review article

    HDAC8: a multifaceted target for therapeutic interventions

    • Alokta Chakrabarti
    • Ina Oehme
    • Olaf Witt
    • Guilherme Oliveira
    • Wolfgang Sippl
    • Christophe Romier
    • Raymond J. Pierce
    • Manfred Jung

    Trends in Pharmacological Sciences ; Volume: 36 ; Page: 481-492

    HALDOI

  • Article in a journal

    Drugging the Schistosome Zinc-Dependent HDACs: Current Progress and Future Perspectives

    • Martin Marek
    • Guilherme Oliveira
    • Raymond J. Pierce
    • Manfred Jung
    • Wolfgang Sippl
    • Christophe Romier

    Future Medicinal Chemistry ; Volume: 7 ; Page: 783--800

    HALDOI

• 2014

  • Article in a journal

    Hydroxamates of para-aminobenzoic acid as selective inhibitors of HDAC8

    • Laxmi Manasa Chilakamari
    • Surender Singh Jadav
    • Tadikonda Rama Rao
    • K.N. Jayaveera
    • Boyapati Shireesha
    • Alexander-Thomas Hauser
    • Johanna Senger
    • Martin Marek
    • Christophe Romier
    • Manfred Jung
    • Venkatesan Jayaprakash

    Bioorganic Chemistry ; Volume: 57 ; Page: 116-120

    HALDOI

  • Article in a journal

    Sequence and structure requirements for specific recognition of HIV-1 TAR and DIS RNA by the HIV-1 Vif protein

    • Séverine Freisz
    • Joelle Mezher
    • Lamine Hafirassou
    • Philippe Wolff
    • Yves Nominé
    • Christophe Romier
    • Philippe Dumas
    • Eric Ennifar

    RNA Biology ; Volume: 9 ; Page: 966-977

    HALDOI

  • Article in a journal

    Discovery of Inhibitors of Schistosoma mansoni HDAC8 by Combining Homology Modeling, Virtual Screening, and in Vitro Validation

    • Srinivasaraghavan Kannan
    • Jelena Melesina
    • Alexander-Thomas Hauser
    • Alokta Chakrabarti
    • Tino Heimburg
    • Karin Schmidtkunz
    • Alexandra Walter
    • Martin Marek
    • Raymond Pierce
    • Christophe Romier
    • Manfred Jung
    • Wolfgang Sippl

    Journal of Chemical Information and Modeling ; Volume: 54 ; Page: 3005-3019

    HALDOI