Congratulations to Yasenya Kasikci on the acceptance of her thesis!

During her thesis, Yasenya Kasikci characterized a deregulated cancer networks, showed the intra-individual heterogeneity between patients and identified potential therapeutics targets for personalized therapy. Using various techniques, they identified differentially expressed genes and mutated genes, then they generated patient-specific networks and pinpointed key nodes involved in the cross-talk between different deregulated pathways. The study highlights the importance of understanding individual patient profiles to guide effective treatment strategies in prostate cancer.

Want to know more ? You can read this article published in the American Journal of Cancer Research: https://pubmed.ncbi.nlm.nih.gov/34873462/

During her time at the IGBMC, the PhD student was able to develop crucial skills in functional genomics, such as high-throughput sequencing and Chip-seq. She also had the opportunity to get experience in cutting edge technologies like Cut&Tag and Cut&Run.

Thanks to our platforms in providing their expertise and supervision for her experiments, thanks to Genomeast (David Rodriguez), Cell culture platform and Mediaprep.

This project was funded by La ligue contre le cancer. During her thesis Yasenya Kasikci also worked on a second project about stem cell and neurobiology which was funded by INCA. Thanks to Centre de recherche en cancérologie de Lyon (Fabrice Lavial) and Genoscope, Paris (Mendoza Parra) for their collaboration.

Yasenya Kasikci will now continue as a Field application scientist, we wish her good luck in this next phase of her career !