Regulation of DNA topology
Team Leaders : Valerie LAMOUR , Marc RUFF
Department : Integrated structural biology
Drug discovery against nosocomial bacteria
Drug discovery against nosocomial bacteria
SUBGROUP LEADER
Teams
Members
Researchers
Publications
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2024
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Integrase-LEDGF/p75 complex triggers the formation of biomolecular condensates that modulate HIV-1 integration efficiency in vitro
- Claire Batisse
- Delphine Lapaillerie
- Nicolas Humbert
- Eleonore Real
- Rui Zhu
- Yves Mély
- Vincent Parissi
- Marc Ruff
- Julien Batisse
Journal of Biological Chemistry ; Volume: 300 ; Page: 107374
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2023
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Biological and Structural Analyses of New Potent Allosteric Inhibitors of HIV-1 Integrase
- Damien Bonnard
- Erwann Le Rouzic
- Matthew Singer
- Zhe Yu
- Frédéric Le Strat
- Claire Batisse
- Julien Batisse
- Céline Amadori
- Sophie Chasset
- Valerie Pye
- Stéphane Emiliani
- Benoit Ledoussal
- Marc Ruff
- François Moreau
- Peter Cherepanov
- Richard Benarous
Antimicrobial Agents and Chemotherapy ; Volume: 67
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The kinesin Kif21b regulates radial migration of cortical projection neurons through a non-canonical function on actin cytoskeleton
- José Rivera Alvarez
- Laure Asselin
- Peggy Tilly
- Roxane Benoit
- Claire Batisse
- Ludovic Richert
- Julien Batisse
- Bastien Morlet
- Florian Levet
- Noémie Schwaller
- Yves Mély
- M. Ruff
- Anne-Cécile Reymann
- Juliette Godin
Cell Reports ; Volume: 42 ; Page: 112744
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2022
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Efficient production of protein complexes in mammalian cells using a poxvirus vector
- Robert Drillien
- Karine Pradeau Aubreton
- Julien Batisse
- Joelle Mezher
- Emma Schenckbecher
- Justine Marguin
- Eric Ennifar
- Marc Ruff
PLoS ONE ; Volume: 17
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The HIV-1 Integrase C-Terminal domain induces TAR RNA structural changes promoting Tat binding
- Cecilia Rocchi
- Camille Louvat
- Adriana Miele
- Julien Batisse
- Christophe Guillon
- Lionel Ballut
- Daniela Lener
- Matteo Negroni
- Marc Ruff
- Patrice Gouet
- Francesca Fiorini
International Journal of Molecular Sciences ; Volume: 23 ; Page: 13742
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Efficient production of protein complexes in mammalian cells using a poxvirus vector
- Robert Drillien
- Karine Pradeau-Aubreton
- Julien Batisse
- Joëlle Mezher
- Emma Schenckbecher
- Justine Marguin
- Eric Ennifar
- Marc Ruff
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Thienoguanosine brightness in DNA duplexes is governed by the localization of itsππ* excitation in the lowest energy absorption band
- Stefano Ciaco
- Krishna Gavvala
- Vanille Greiner
- Viola Mazzoleni
- Pascal Didier
- Marc Ruff
- Lara Martinez-Fernandez
- Roberto Improta
- Yves Mély
Methods and Applications in Fluorescence ; Volume: 10
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HRAS germline mutations impair LKB1/AMPK signaling and mitochondrial homeostasis in Costello syndrome models
- Laetitia Dard
- Christophe Hubert
- Pauline Esteves
- Wendy Blanchard
- Ghina Bou About
- Lyla Baldasseroni
- Elodie Dumon
- Chloe Angelini
- Mégane Delourme
- Veronique Guyonnet-Duperat
- Stephane Claverol
- Laura Fontenille
- Karima Kissa
- Pierre-Emmanuel Seguela
- Jean-Benoit Thambo
- Nicolas Levy
- Yann Hérault
- Nadege Bellance
- Nivea Dias Amoedo
- Frédérique Magdinier
- ...
JOURNAL OF CLINICAL INVESTIGATION ; Volume: 132
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2021
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The HIV-1 Integrase C-Terminal domain induces TAR RNA structural changes promoting Tat binding
- Cecilia Rocchi
- Camille Louvat
- Adriana Miele
- Julien Batisse
- Christophe Guillon
- Lionel Ballut
- Daniela Lener
- Matteo Negroni
- Marc Ruff
- Patrice Gouet
- Francesca Fiorini
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Modulation of the intrinsic chromatin binding property of HIV-1 integrase by LEDGF/p75
- Delphine Lapaillerie
- Benoît Lelandais
- Eric Mauro
- Floriane Lagadec
- Camille Tumiotto
- Csaba Miskey
- Guillaume Ferran
- Natacha Kuschner
- Christina Calmels
- Mathieu Métifiot
- Caroline Rooryck
- Zoltan Ivics
- Marc Ruff
- Christophe Zimmer
- Paul Lesbats
- Jérôme Toutain
- Vincent Parissi
Nucleic Acids Research ; Volume: 49 ; Page: 11241-11256
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