
Cell physics
Cell physics
The Cell Physics team characterizes self-organization of cells, cell motion, cell division, morphogenesis of tissues in vitro and in vivo. The projects involve synergized approaches between theoretical physics, cell biology, microfabrication.
For more details, see : riveline.igbmc.science
Members
Researchers
PhD students
Current projects
Self-organisation in living matter : from cell motility and cytokinesis to morphogenesis
- Cell motility: Ratchetaxis and Scallop Theorem
Publications.
How a cell moves from a point A to a point B in the absence of long range gradient.
- Lammelipodia growth promoter: supramolecular compounds specific to actin
Publications.
Synthetic polyamines trigger growth of lamellipodia within minutes (scale bar 20μm).
- Cytokinesis: myosin clusters dynamics and rings constriction across systems
Publications.
Myosin clusters dynamics determine the evolutions of cytokinetic rings visualized in a single focal plane with micro-fabricated cavities (myosin, scale bar 5μm).
- Morphogenesis in vitro: collective effects in cells
Publications.
Elongation of an epithelial colony results from nematic fields and topological defects (scale bar 50μm).
- Scaling and injections of fission yeast
Publications.
Asymmetric division : Scaling arguments predict the localisation of septum correlated with differences in cell ends (left).
Fission yeast behaves as a balloon and can be injected (right, scale bar 5μm).
- Reinforcement of focal contacts and cell-cell junctions (adherens junctions and hemidesmosomes)
Publications.
Adhesive contacts elongate with local forces within minutes (compare top and bottom, scale bar 5μm).
They recruit adhesion proteins while keeping their matter density constant.
For more details see : riveline.igbmc.science
Collaborations and networks
- HFSP coordinator 2018 with Alf Honigmann (MPI-CBG Dresden), Anne Grapin-Botton (Danstem, Copenhagen), Masaki Sano (University of Tokyo)
- SNF 2019 with Olivier Pertz (University of Bern), Damian Brunner (University of Zurich), Karsten Kruse (University of Geneva)
Funding and partners
- HFSP coordinator 2018 with Alf Honigmann (MPI-CBG Dresden), Anne Grapin-Botton (Danstem, Copenhagen), Masaki Sano (University of Tokyo)
- SNF 2019 with Olivier Pertz (University of Bern), Damian Brunner (University of Zurich), Karsten Kruse (University of Geneva)
News

A dashboard to study cell movement
Individual cells move in vivo in complex 3D environments. Their motion occurs at zero force and requires symmetry breaking. In this study at the…
Read more
Awards and recognitions
- HFSP coordinator 2018
- Fellowship Simone et Cino del Duca 2011
- ATIP CNRS 2010
Resources
See the website for the Cell Physics Master at the University of Strasbourg
Publications
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2024
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Tight junctions control lumen morphology via hydrostatic pressure and junctional tension
- Markus Mukenhirn
- Chen-Ho Wang
- Tristan Guyomar
- Matthew Bovyn
- Michael Staddon
- Rozemarijn van der Veen
- Riccardo Maraspini
- Linjie Lu
- Cecilie Martin-Lemaitre
- Masaki Sano
- Martin Lehmann
- Tetsuya Hiraiwa
- Daniel Riveline
- Alf Honigmann
Developmental Cell ; Volume: 59 ; Page: 2866-2881.e8
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Myosin cluster dynamics determines epithelial wound ring constriction
- Alka Bhat
- Remi Berthoz
- Simon Lo Vecchio
- Coralie Spiegelhalter
- Shigenobu Yonemura
- Olivier Pertz
- Daniel Riveline
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Asymmetry of acto-myosin cortices as active fluids shape cells in organoids
- Tristan Guyomar
- Linjie Lu
- Tetsuya Hiraiwa
- Daniel Riveline
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Control of lumen geometry and topology by the interplay between pressure and cell proliferation rate in pancreatic organoids
- Byung Ho Lee
- Kana Fuji
- Heike Petzold
- Phil Seymour
- Siham Yennek
- Coline Schewin
- Allison Lewis
- Daniel Riveline
- Tetsuya Hiraiwa
- Masaki Sano
- Anne Grapin-Botton
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Polarity-driven three-dimensional spontaneous rotation of a cell doublet
- Linjie Lu
- Tristan Guyomar
- Quentin Vagne
- Rémi Berthoz
- Alejandro Torres-Sánchez
- Michele Lieb
- Cecilie Martin-Lemaitre
- Kobus van Unen
- Alf Honigmann
- Olivier Pertz
- Daniel Riveline
- Guillaume Salbreux
Nature Physics ; Volume: 20 ; Page: 1194-1203
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Spontaneous rotations in epithelia as an interplay between cell polarity and boundaries
- Simon Lo Vecchio
- Olivier Pertz
- Marcela Szopos
- Laurent Navoret
- Daniel Riveline
Nature Physics
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2023
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The interplay between lumen pressure and cell proliferation determines organoid morphology in a multicellular phase field model
- Sakurako Tanida
- Kana Fuji
- Linjie Lu
- Tristan Guyomar
- Byung Ho Lee
- Alf Honigmann
- Anne Grapin-Botton
- Daniel Riveline
- Tetsuya Hiraiwa
- Makiko Nonomura
- Masaki Sano
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The interplay between lumen pressure and cell proliferation determines organoid morphology in a multicellular phase field model
- Sakurako Tanida
- Kana Fuji
- Linjie Lu
- Tristan Guyomar
- Byung Ho Lee
- Alf Honigmann
- Anne Grapin-Botton
- Daniel Riveline
- Tetsuya Hiraiwa
- Makiko Nonomura
- Masaki Sano
-
Tight junctions regulate lumen morphology via hydrostatic pressure and junctional tension
- Markus Mukenhirn
- Chen-Ho Wang
- Tristan Guyomar
- Matthew J Bovyn
- Michael F Staddon
- Riccardo Maraspini
- Linjie Lu
- Cecilie Martin-Lemaitre
- Masaki Sano
- Tetsuya Hiraiwa
- Daniel Riveline
- Alf Honigmann
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2022
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Polarity-driven three-dimensional spontaneous rotation of a cell doublet
- Linjie Lu
- Tristan Guyomar
- Quentin Vagne
- Rémi Berthoz
- Alejandro Torres-Sánchez
- Michèle Lieb
- Cecilie Martin-Lemaitre
- Kobus van Unen
- Alf Honigmann
- Olivier Pertz
- Guillaume Salbreux
- Daniel Riveline
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