Regulation of DNA topology
Team Leaders : Valerie LAMOUR , Marc RUFF
Department : Integrated structural biology
Structure function of complexes involved in the HIV replication cycle, drug design
Structure function of complexes involved in the HIV replication cycle, drug design
SUBGROUP LEADER
Teams
Members
Publications
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2022
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Article in a journal
HRAS germline mutations impair LKB1/AMPK signaling and mitochondrial homeostasis in Costello syndrome models
- Laetitia Dard
- Christophe Hubert
- Pauline Esteves
- Wendy Blanchard
- Ghina Bou About
- Lyla Baldasseroni
- Elodie Dumon
- Chloe Angelini
- Mégane Delourme
- Veronique Guyonnet-Duperat
- Stephane Claverol
- Laura Fontenille
- Karima Kissa
- Pierre-Emmanuel Seguela
- Jean-Benoit Thambo
- Nicolas Levy
- Yann Hérault
- Nadege Bellance
- Nivea Dias Amoedo
- Frédérique Magdinier
- ...
JOURNAL OF CLINICAL INVESTIGATION ; Volume: 132
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2020
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Article in a journal
NKNK: a New Essential Motif in the C-Terminal Domain of HIV-1 Group M Integrases
- Marine Kanja
- Pierre Cappy
- Nicolas Levy
- Oyindamola Oladosu
- Sylvie Schmidt
- Paola Rossolillo
- Flore Winter
- Romain Gasser
- Christiane Moog
- Marc Ruff
- Matteo Negroni
- Daniela Lener-Ory
Journal of Virology ; Volume: 94
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Article in a journal
Structural and Functional Studies of Human Type II Topoisomerases and their Post-Translational Modifications
- Christophe Lotz
- Claire Bedez
- Claire Batisse
- Arnaud Vanden Broeck
- Drillien Robert
- Marc Ruff
- Valerie Lamour
Biophysical Journal ; Volume: 118 ; Page: 532a
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Article in a journal
HIV-1 Pre-Integration Complexes. Structures, Functions and Drug Design
- Julien Batisse
- Eduardo Bruch
- Nicolas Levy
- Sylvia Eiler
- Sylvie Duclaud
- Patrick Schultz
- Patrice Gouet
- Serge Bouaziz
- Olivier Delelis
- Vincent Parissi
- Marc Ruff
Biophysical Journal ; Volume: 118 ; Page: 500a
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2019
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Article in a journal
A Molecular Tool Targeting the Base‐Flipping Activity of Human UHRF1
- Liliyana Zaayter
- Mattia Mori
- Tanveer Ahmad
- Waseem Ashraf
- Christian Boudier
- Vasyl Kilin
- Krishna Gavvala
- Ludovic Richert
- Sylvia Eiler
- Marc Ruff
- Maurizio Botta
- Christian Bronner
- Marc Mousli
- Yves Mély
Chemistry - A European Journal ; Volume: 25 ; Page: 13363-13375
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Article in a journal
HSPA8/HSC70 in Immune Disorders: A Molecular Rheostat that Adjusts Chaperone-Mediated Autophagy Substrates
- Srinivasa Reddy Bonam
- Marc Ruff
- Sylviane Muller
Cells ; Volume: 8 ; Page: 849
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Article in a journal
Human H4 tail stimulates HIV-1 integration through binding to the carboxy-terminal domain of integrase
- Eric Mauro
- Paul Lesbats
- Delphine Lapaillerie
- Stéphane Chaignepain
- Benoit Maillot
- Oyindamola Oladosu
- Xavier Robert
- Francesca Fiorini
- Bruno Kieffer
- Serge Bouaziz
- Patrice Gouet
- Marc Ruff
- Vincent Parissi
Nucleic Acids Research ; Volume: 47 ; Page: 3607-3618
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Article in a journal
Structural Basis for E. coli Penicillin Binding Protein (PBP) 2 Inhibition, a Platform for Drug Design
- Nicolas Lévy
- Jean-Michel Bruneau
- Erwann Le Rouzic
- Damien Bonnard
- Frédéric Le Strat
- Audrey Caravano
- Francis Chevreuil
- Julien Barbion
- Sophie Chasset
- Benoit Ledoussal
- François Moreau
- Marc Ruff
Journal of Medicinal Chemistry ; Volume: 62 ; Page: 4742-4754
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Article in a journal
Structures and Functions of the HIV-1 Pre-Integration Complexes
- Julien Batisse
- Eduardo Bruch
- Nicolas Lévy
- Patrice Gouet
- Stéphane Emiliani
- Vincent Parissi
- Marc Ruff
Biophysical Journal ; Volume: 116 ; Page: 62a
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2018
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Article in a journal
Post-translational modifications in DNA topoisomerase 2α highlight the role of a eukaryote-specific residue in the ATPase domain
- Claire Bedez
- Christophe Lotz
- Claire Batisse
- Arnaud Vanden Broeck
- Roland Stote
- Eduardo Howard
- Karine Pradeau Aubreton
- Marc Ruff
- Valerie Lamour
Scientific Reports ; Volume: 8
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