Christophe ROMIER

Publications

• 2015

  • Drugging the Schistosome Zinc-Dependent HDACs: Current Progress and Future Perspectives

    • Martin Marek
    • Guilherme Oliveira
    • Raymond J. Pierce
    • Manfred Jung
    • Wolfgang Sippl
    • Christophe Romier

    Future Medicinal Chemistry ; Volume: 7 ; Page: 783--800

    HAL DOI

  • HDAC8: a multifaceted target for therapeutic interventions

    • Alokta Chakrabarti
    • Ina Oehme
    • Olaf Witt
    • Guilherme Oliveira
    • Wolfgang Sippl
    • Christophe Romier
    • Raymond J. Pierce
    • Manfred Jung

    Trends in Pharmacological Sciences ; Volume: 36 ; Page: 481-492

    HAL DOI

  • Homology modeling of parasite histone deacetylases to guide the structure-based design of selective inhibitors

    • Jelena Melesina
    • Dina Robaa
    • Raymond J. Pierce
    • Christophe Romier
    • Wolfgang Sippl

    Journal of Molecular Graphics and Modelling ; Volume: 62 ; Page: 342--361

    HAL DOI

• 2014

  • Hydroxamates of para-aminobenzoic acid as selective inhibitors of HDAC8

    • Laxmi Manasa Chilakamari
    • Surender Singh Jadav
    • Tadikonda Rama Rao
    • K.N. Jayaveera
    • Boyapati Shireesha
    • Alexander-Thomas Hauser
    • Johanna Senger
    • Martin Marek
    • Christophe Romier
    • Manfred Jung
    • Venkatesan Jayaprakash

    Bioorganic Chemistry ; Volume: 57 ; Page: 116-120

    HAL DOI

  • Sequence and structure requirements for specific recognition of HIV-1 TAR and DIS RNA by the HIV-1 Vif protein

    • Séverine Freisz
    • Joelle Mezher
    • Lamine Hafirassou
    • Philippe Wolff
    • Yves Nominé
    • Christophe Romier
    • Philippe Dumas
    • Eric Ennifar

    RNA Biology ; Volume: 9 ; Page: 966-977

    HAL DOI

  • Discovery of Inhibitors of Schistosoma mansoni HDAC8 by Combining Homology Modeling, Virtual Screening, and in Vitro Validation

    • Srinivasaraghavan Kannan
    • Jelena Melesina
    • Alexander-Thomas Hauser
    • Alokta Chakrabarti
    • Tino Heimburg
    • Karin Schmidtkunz
    • Alexandra Walter
    • Martin Marek
    • Raymond Pierce
    • Christophe Romier
    • Manfred Jung
    • Wolfgang Sippl

    Journal of Chemical Information and Modeling ; Volume: 54 ; Page: 3005-3019

    HAL DOI

  • Characterization of the interaction between protein Snu13p/15.5K and the Rsa1p/NUFIP factor and demonstration of its functional importance for snoRNP assembly

    • Benjamin Rothé
    • Régis Back
    • Marc Quinternet
    • Jonathan Bizarro
    • Marie-Cécile Robert
    • Magali Blaud
    • Christophe Romier
    • Xavier Manival
    • Bruno Charpentier
    • Edouard Bertrand
    • Christiane Branlant

    Nucleic Acids Research ; Volume: 42 ; Page: 2015-2036

    HAL DOI

  • TAF4, a subunit of transcription factor II D, directs promoter occupancy of nuclear receptor HNF4A during post-natal hepatocyte differentiation

    • Daniil Alpern
    • Diana Langer
    • Benoit Ballester
    • Stephanie Le Gras
    • Christophe Romier
    • Gabrielle Mengus
    • Irwin Davidson

    eLife ; Volume: 3 ; Page: 308-312

    HAL DOI

  • DNA Binding by Sgf11 Protein Affects Histone H2B Deubiquitination by Spt-Ada-Gcn5-Acetyltransferase (SAGA)

    • Christian Koehler
    • Jacques Bonnet
    • Matthieu Stierle
    • Christophe Romier
    • Didier Devys
    • Bruno Kieffer

    Journal of Biological Chemistry ; Volume: 289 ; Page: 8989 - 8999

    HAL DOI

  • Molecular basis for the antiparasitic activity of a mercaptoacetamide derivative that inhibits histone deacetylase 8 (HDAC8) from the human pathogen schistosoma mansoni

    • D Stolfa
    • Martin Marek
    • J Lancelot
    • A Hauser
    • A Walter
    • E Leproult
    • J Melesina
    • T Rumpf
    • Jean-Marie Wurtz
    • Jean Cavarelli
    • W Sippl
    • R Pierce
    • Christophe Romier
    • Matthieu Jung

    Journal of Molecular Biology ; Volume: 426 ; Page: 3442-3453

    HAL DOI