Pathophysiology of Down's syndrome and rare dose-effect diseases causing intellectual disabilities (ID) or autism spectrum disorders (ASD) and other comorbidities
Team Leader : Yann HERAULT
Department : Translational medecine and neurogenetics
Michel ROUX
Researcher
michel.roux@igbmc.fr
Research team(s)
Publications
2025
Article in a journal
Ocular Phenotyping of Knockout Mice Identifies Genes Associated With Late Adult Retinal Phenotypes
- Abraham Hang
- Andy Shao
- Michael Shea
- Michel Roux
- Denise Imai-Leonard
- David Adams
- Takanori Amano
- Oana Amarie
- Zorana Berberovic
- Raphaël Bour
- Lynette Bower
- Brian Leonard
- Steve Brown
- Soo Young Cho
- Sharon Clementson-Mobbs
- Abigail d'Souza
- Mary Dickinson
- Mohammad Eskandarian
- Ann Flenniken
- Helmut Fuchs
- ...
Investigative Ophthalmology & Visual Science ; Volume: 66 ; Page: 64
Article in a journal
Systematic Ocular Phenotyping of Knockout Mouse Lines Identifies Genes Associated With Age-Related Corneal Dystrophies
- Andrew Briere
- Peter Vo
- Benjamin Yang
- David Adams
- Takanori Amano
- Oana Amarie
- Zorana Berberovic
- Lynette Bower
- Steve Brown
- Samantha Burrill
- Soo Young Cho
- Sharon Clementson-Mobbs
- Abigail d'Souza
- Mohammad Eskandarian
- Ann Flenniken
- Helmut Fuchs
- Valerie Gailus-Durner
- Yann Hérault
- Martin Hrabe de Angelis
- Shundan Jin
- ...
Investigative Ophthalmology & Visual Science ; Volume: 66 ; Page: 7
Article in a journal
Systematic ocular phenotyping of 8,707 knockout mouse lines identifies genes associated with abnormal corneal phenotypes
- Peter Vo
- Denise Imai-Leonard
- Benjamin Yang
- Andrew Briere
- Andy Shao
- M. Isabel Casanova
- David Adams
- Takanori Amano
- Oana Amarie
- Zorana Berberovic
- Lynette Bower
- Robert Braun
- Steve Brown
- Samantha Burrill
- Soo Young Cho
- Sharon Clementson-Mobbs
- Abigail D’souza
- Mary Dickinson
- Mohammad Eskandarian
- Ann Flenniken
- ...
BMC Genomics ; Volume: 26 ; Page: 48
2024
Article in a journal
Interruption of the visual cycle in a novel animal model induces progressive vision loss resembling Stargardts Disease
- Fabiana Sassone
- Catherine Estay-Ahumada
- Michel J. Roux
- Dominique Ciocca
- Paola Rossolillo
- Marie-Christine Birling
- Janet R Sparrow
- Diego Montenegro
- David Hicks
Scientific Reports ; Volume: 14 ; Page: 30880
Article in a journal
Hyperglycemia and circadian disruption lead to retinal dysfunction in a stabilized colony of the fat sand rat Psammomys obesus
- Catherine Estay-Ahumada
- Daniela Verra
- Michel Roux
- Fabiana Sassone
- Marie-Paule Felder-Schmittbuhl
- Christophe Klopp
- Dominique Ciocca
- Myriam Ly-Le Moal
- David Hicks
Biochimica et Biophysica Acta - Molecular Basis of Disease ; Volume: 1870 ; Page: 167118
2023
Pre-publication, Working Document
Abca4 inhibition in a cone-rich rodent leads to Stargardt Disease type 1-like retinal degeneration
- Fabiana Sassone
- Michel J. Roux
- Dominique Ciocca
- Paola Rossolillo
- Marie-Christine Birling
- Janet Sparrow
- David Hicks
Article in a journal
Retinal dystrophins and the retinopathy of Duchenne muscular dystrophy
- Mirella Telles Salgueiro Barboni
- Anneka Joachimsthaler
- Michel Roux
- Zoltán Zsolt Nagy
- Dora Fix Ventura
- Alvaro Rendon
- Jan Kremers
- Cyrille Vaillend
Progress in Retinal and Eye Research ; Page: 101137
2022
Article in a journal
Polyglutamine-expanded ATXN7 alters a specific epigenetic signature underlying photoreceptor identity gene expression in SCA7 mouse retinopathy
- Anna Niewiadomska-Cimicka
- Antoine Hache
- Stéphanie Le Gras
- Céline Keime
- Tao Ye
- Aurelie Eisenmann
- Imen Harichane
- Michel Roux
- Nadia Messaddeq
- Emmanuelle Clérin
- Thierry Léveillard
- Yvon Trottier
Journal of Biomedical Science ; Volume: 107
2021
Article in a journal
SCA7 Mouse Cerebellar Pathology Reveals Preferential Downregulation of Key Purkinje Cell-Identity Genes and Shared Disease Signature with SCA1 and SCA2
- Anna Niewiadomska-Cimicka
- Frédéric Doussau
- Jean-Baptiste Perot
- Michel Roux
- Celine Keime
- Antoine Hache
- Françoise Piguet
- Ariana Novati
- Chantal Weber
- Binnaz Yalcin
- Hamid Meziane
- Marie-France Champy
- Erwan Grandgirard
- Alice Karam
- Nadia Messaddeq
- Aurélie Eisenmann
- Emmanuel Brouillet
- Hoa Huu Phuc Nguyen
- Julien Flament
- Philippe Isope
- ...
Journal of Neuroscience ; Volume: 41 ; Page: 4910-4936
2020
Article in a journal
Rescue of Defective Electroretinographic Responses in Dp71-Null Mice With AAV-Mediated Reexpression of Dp71
- Mirella Telles Salgueiro Barboni
- Cyrille Vaillend
- Anneka Joachimsthaler
- André Maurício Passos Liber
- Hanen Khabou
- Michel Roux
- Ophélie Vacca
- Lucile Vignaud
- Deniz Dalkara
- Xavier Guillonneau
- Jan Kremers
- Dora Fix Ventura
- Alvaro Rendon
Investigative Ophthalmology & Visual Science ; Volume: 61 ; Page: 11