Pathophysiology of Down's syndrome and rare dose-effect diseases causing intellectual disabilities (ID) or autism spectrum disorders (ASD) and other comorbidities
Team Leader : Yann HERAULT
Department : Translational medecine and neurogenetics
Michel ROUX
Researcher
michel.roux@igbmc.fr
Research team(s)
Publications
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2024
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Interruption of the visual cycle in a novel animal model induces progressive vision loss resembling Stargardts Disease
- Fabiana Sassone
- Catherine Estay-Ahumada
- Michel J. Roux
- Dominique Ciocca
- Paola Rossolillo
- Marie-Christine Birling
- Janet R Sparrow
- Diego Montenegro
- David Hicks
Scientific Reports ; Volume: 14 ; Page: 30880
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Hyperglycemia and circadian disruption lead to retinal dysfunction in a stabilized colony of the fat sand rat Psammomys obesus
- Catherine Estay-Ahumada
- Daniela Verra
- Michel Roux
- Fabiana Sassone
- Marie-Paule Felder-Schmittbuhl
- Christophe Klopp
- Dominique Ciocca
- Myriam Ly-Le Moal
- David Hicks
Biochimica et Biophysica Acta - Molecular Basis of Disease ; Volume: 1870 ; Page: 167118
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2023
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Abca4 inhibition in a cone-rich rodent leads to Stargardt Disease type 1-like retinal degeneration
- Fabiana Sassone
- Michel J. Roux
- Dominique Ciocca
- Paola Rossolillo
- Marie-Christine Birling
- Janet Sparrow
- David Hicks
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Retinal dystrophins and the retinopathy of Duchenne muscular dystrophy
- Mirella Telles Salgueiro Barboni
- Anneka Joachimsthaler
- Michel Roux
- Zoltán Zsolt Nagy
- Dora Fix Ventura
- Alvaro Rendon
- Jan Kremers
- Cyrille Vaillend
Progress in Retinal and Eye Research ; Page: 101137
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2022
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Polyglutamine-expanded ATXN7 alters a specific epigenetic signature underlying photoreceptor identity gene expression in SCA7 mouse retinopathy
- Anna Niewiadomska-Cimicka
- Antoine Hache
- Stéphanie Le Gras
- Céline Keime
- Tao Ye
- Aurelie Eisenmann
- Imen Harichane
- Michel Roux
- Nadia Messaddeq
- Emmanuelle Clérin
- Thierry Léveillard
- Yvon Trottier
Journal of Biomedical Science ; Volume: 107
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2021
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SCA7 Mouse Cerebellar Pathology Reveals Preferential Downregulation of Key Purkinje Cell-Identity Genes and Shared Disease Signature with SCA1 and SCA2
- Anna Niewiadomska-Cimicka
- Frédéric Doussau
- Jean-Baptiste Perot
- Michel Roux
- Celine Keime
- Antoine Hache
- Françoise Piguet
- Ariana Novati
- Chantal Weber
- Binnaz Yalcin
- Hamid Meziane
- Marie-France Champy
- Erwan Grandgirard
- Alice Karam
- Nadia Messaddeq
- Aurélie Eisenmann
- Emmanuel Brouillet
- Hoa Huu Phuc Nguyen
- Julien Flament
- Philippe Isope
- ...
Journal of Neuroscience ; Volume: 41 ; Page: 4910-4936
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2020
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Rescue of Defective Electroretinographic Responses in Dp71-Null Mice With AAV-Mediated Reexpression of Dp71
- Mirella Telles Salgueiro Barboni
- Cyrille Vaillend
- Anneka Joachimsthaler
- André Maurício Passos Liber
- Hanen Khabou
- Michel Roux
- Ophélie Vacca
- Lucile Vignaud
- Deniz Dalkara
- Xavier Guillonneau
- Jan Kremers
- Dora Fix Ventura
- Alvaro Rendon
Investigative Ophthalmology & Visual Science ; Volume: 61 ; Page: 11
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2019
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In vivo phenotypic and molecular characterization of retinal degeneration in mouse models of three ciliopathies
- Agnès Brun
- Xiangxiang Yu
- Cathy Obringer
- Daniel Ajoy
- Elodie Haser
- Corinne Stoetzel
- Michel J Roux
- Nadia Messaddeq
- Hélène Dollfus
- Vincent Marion
Experimental Eye Research ; Volume: 186 ; Page: 107721
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Evidence for functional GABAA but not GABAC receptors on mouse cone photoreceptors
- Sercan Deniz
- Eric Wersinger
- Serge Picaud
- Michel J Roux
Visual Neuroscience ; Volume: 36 ; Page: E005
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Erratum: Author Correction: Identification of genes required for eye development by high-throughput screening of mouse knockouts
- B Moore
- B Leonard
- L Sebbag
- S Edwards
- A Cooper
- D Imai
- E Straiton
- L Santos
- C Reilly
- S Griffey
- L Bower
- D Clary
- J Mason
- Michel Roux
- Hamid Meziane
- Yann Hérault
- C Mckerlie
- A Flenniken
- L Nutter
- Z Berberovic
- ...
Communications Biology ; Volume: 2
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