Regulation of DNA topology
Team Leaders : Valerie LAMOUR , Marc RUFF
Department : Integrated structural biology
Valerie LAMOUR
Researcher
lamourv@igbmc.fr
Research team(s)
Research subgroup(s)
Publications
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2024
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Structural basis of DNA crossover capture by Escherichia coli DNA gyrase
- Marlène Vayssières
- Nils Marechal
- Long Yun
- Brian Lopez Duran
- Naveen Kumar Murugasamy
- Jonathan Fogg
- Lynn Zechiedrich
- Marc Nadal
- Valérie Lamour
Science ; Volume: 384 ; Page: 227-232
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2023
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What’s on the Other Side of the Gate: A Structural Perspective on DNA Gate Opening of Type IA and IIA DNA Topoisomerases
- Vita Vidmar
- Marlène Vayssières
- Valérie Lamour
International Journal of Molecular Sciences ; Volume: 24 ; Page: 3986
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2022
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The human RNA polymerase I structure reveals an HMG-like docking domain specific to metazoans
- Julia L Daiß
- Michael Pilsl
- Kristina Straub
- Andrea Bleckmann
- Mona Höcherl
- Florian B Heiss
- Guillermo Abascal-Palacios
- Ewan P Ramsay
- Katarina Tlučková
- Jean-Clement Mars
- Torben Fürtges
- Astrid Bruckmann
- Till Rudack
- Carrie Bernecky
- Valérie Lamour
- Konstantin Panov
- Alessandro Vannini
- Tom Moss
- Christoph Engel
Life Science Alliance ; Volume: 5 ; Page: e202201568
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2021
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Structural basis for allosteric regulation of Human Topoisomerase IIα
- Arnaud Vanden Broeck
- Christophe Lotz
- Robert Drillien
- Léa Haas
- Claire Bedez
- Valérie Lamour
Nature Communications ; Volume: 12
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Exonuclease VII repairs quinolone-induced damage by resolving DNA gyrase cleavage complexes
- Shar-Yin N. Huang
- Stephanie A. Michaels
- Brianna B. Mitchell
- Nadim Majdalani
- Arnaud Vanden Broeck
- Andres Canela
- Yuk-Ching Tse-Dinh
- Valérie Lamour
- Yves Pommier
Science Advances ; Volume: 7 ; Page: eabe0384
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2020
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Structural and Functional Studies of Human Type II Topoisomerases and their Post-Translational Modifications
- Christophe Lotz
- Claire Bedez
- Claire Batisse
- Arnaud Vanden Broeck
- Drillien Robert
- Marc Ruff
- Valerie Lamour
Biophysical Journal ; Volume: 118 ; Page: 532a
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The interplay between DNA topoisomerase 2α post-translational modifications and drug resistance
- Christophe Lotz
- Valerie Lamour
Cancer Drug Resistance ; Page: 149-160
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2019
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Cryo-EM structure of the complete E. coli DNA gyrase nucleoprotein complex
- Arnaud Vanden Broeck
- Christophe Lotz
- Julio Ortiz Espinoza
- Valerie Lamour
Nature Communications ; Volume: 10 ; Page: 4935
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2018
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Post-translational modifications in DNA topoisomerase 2α highlight the role of a eukaryote-specific residue in the ATPase domain
- Claire Bedez
- Christophe Lotz
- Claire Batisse
- Arnaud Vanden Broeck
- Roland Stote
- Eduardo Howard
- Karine Pradeau Aubreton
- Marc Ruff
- Valerie Lamour
Scientific Reports ; Volume: 8
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Structural Basis for DNA Gyrase Interaction with Coumermycin A1
- Arnaud Vanden Broeck
- Alastair G Mcewen
- Yassmine Chebaro
- Noelle Potier
- Valerie Lamour
Journal of Medicinal Chemistry ; Volume: 62 ; Page: 4225-4231
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