Drug discovery against nosocomial bacteria

Publications

• 2020

  • NKNK: a New Essential Motif in the C-Terminal Domain of HIV-1 Group M Integrases

    • Marine Kanja
    • Pierre Cappy
    • Nicolas Levy
    • Oyindamola Oladosu
    • Sylvie Schmidt
    • Paola Rossolillo
    • Flore Winter
    • Romain Gasser
    • Christiane Moog
    • Marc Ruff
    • Matteo Negroni
    • Daniela Lener-Ory

    Journal of Virology ; Volume: 94

    HAL DOI

  • Structural and Functional Studies of Human Type II Topoisomerases and their Post-Translational Modifications

    • Christophe Lotz
    • Claire Bedez
    • Claire Batisse
    • Arnaud Vanden Broeck
    • Drillien Robert
    • Marc Ruff
    • Valerie Lamour

    Biophysical Journal ; Volume: 118 ; Page: 532a

    HAL DOI

  • HIV-1 Pre-Integration Complexes. Structures, Functions and Drug Design

    • Julien Batisse
    • Eduardo Bruch
    • Nicolas Lévy
    • Sylvia Eiler
    • Sylvie Duclaud
    • Patrick Schultz
    • Patrice Gouet
    • Serge Bouaziz
    • Olivier Delelis
    • Vincent Parissi
    • M. Ruff

    HAL

  • HIV-1 Pre-Integration Complexes. Structures, Functions and Drug Design

    • Julien Batisse
    • Eduardo Bruch
    • Nicolas Levy
    • Sylvia Eiler
    • Sylvie Duclaud
    • Patrick Schultz
    • Patrice Gouet
    • Serge Bouaziz
    • Olivier Delelis
    • Vincent Parissi
    • Marc Ruff

    Biophysical Journal ; Volume: 118 ; Page: 500a

    HAL DOI

• 2019

  • A Molecular Tool Targeting the Base‐Flipping Activity of Human UHRF1

    • Liliyana Zaayter
    • Mattia Mori
    • Tanveer Ahmad
    • Waseem Ashraf
    • Christian Boudier
    • Vasyl Kilin
    • Krishna Gavvala
    • Ludovic Richert
    • Sylvia Eiler
    • Marc Ruff
    • Maurizio Botta
    • Christian Bronner
    • Marc Mousli
    • Yves Mély

    Chemistry - A European Journal ; Volume: 25 ; Page: 13363-13375

    HAL DOI

  • HSPA8/HSC70 in Immune Disorders: A Molecular Rheostat that Adjusts Chaperone-Mediated Autophagy Substrates

    • Srinivasa Reddy Bonam
    • Marc Ruff
    • Sylviane Muller

    Cells ; Volume: 8 ; Page: 849

    HAL DOI

  • Human H4 tail stimulates HIV-1 integration through binding to the carboxy-terminal domain of integrase

    • Eric Mauro
    • Paul Lesbats
    • Delphine Lapaillerie
    • Stéphane Chaignepain
    • Benoit Maillot
    • Oyindamola Oladosu
    • Xavier Robert
    • Francesca Fiorini
    • Bruno Kieffer
    • Serge Bouaziz
    • Patrice Gouet
    • Marc Ruff
    • Vincent Parissi

    Nucleic Acids Research ; Volume: 47 ; Page: 3607-3618

    HAL DOI

  • Structural Basis for E. coli Penicillin Binding Protein (PBP) 2 Inhibition, a Platform for Drug Design

    • Nicolas Lévy
    • Jean-Michel Bruneau
    • Erwann Le Rouzic
    • Damien Bonnard
    • Frédéric Le Strat
    • Audrey Caravano
    • Francis Chevreuil
    • Julien Barbion
    • Sophie Chasset
    • Benoit Ledoussal
    • François Moreau
    • Marc Ruff

    Journal of Medicinal Chemistry ; Volume: 62 ; Page: 4742-4754

    HAL DOI

  • Structures and Functions of the HIV-1 Pre-Integration Complexes

    • Julien Batisse
    • Eduardo Bruch
    • Nicolas Lévy
    • Patrice Gouet
    • Stéphane Emiliani
    • Vincent Parissi
    • Marc Ruff

    Biophysical Journal ; Volume: 116 ; Page: 62a

    HAL DOI

• 2018

  • Post-translational modifications in DNA topoisomerase 2α highlight the role of a eukaryote-specific residue in the ATPase domain

    • Claire Bedez
    • Christophe Lotz
    • Claire Batisse
    • Arnaud Vanden Broeck
    • Roland Stote
    • Eduardo Howard
    • Karine Pradeau Aubreton
    • Marc Ruff
    • Valerie Lamour

    Scientific Reports ; Volume: 8

    HAL DOI