Molecular and Translational Oncology
Molecular and Translational Oncology
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ARTIFICIAL INTELLIGENCE (AI) SERVING THE HEALTHCARE OF TOMORROW.
Artificial intelligence (AI) has become a key tool in research. Capable of analyzing vast amounts of data, it is opening up new avenues that three…
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Publications
2025
Article in a journal
TFE3 fusions drive oxidative metabolism and ferroptosis resistance in translocation renal cell carcinoma
- Alexandra Helleux
- Guillaume Davidson
- Antonin Lallement
- Fatima Al Hourani
- Alexandre Haller
- Isabelle Michel
- Anas Fadloun
- Christelle Thibault-Carpentier
- Xiaoping Su
- Véronique Lindner
- Thibault Tricard
- Hervé Lang
- Nizar M Tannir
- Irwin Davidson
- Gabriel G Malouf
EMBO Molecular Medicine ; Volume: 17 ; Page: 1041-1070
2023
Article in a journal
Delineating the interplay between oncogenic pathways and immunity in anaplastic Wilms tumors
- Xiaoping Su
- Xiaofan Lu
- Sehrish Khan Bazai
- Linda Dainese
- Arnauld Verschuur
- Benoit Dumont
- Roger Mouawad
- Li Xu
- Wenxuan Cheng
- Fangrong Yan
- Sabine Irtan
- Veronique Lindner
- Catherine Paillard
- Yves Le Bouc
- Aurore Coulomb
- Gabriel Malouf
Nature Communications ; Volume: 14 ; Page: 7884
Article in a journal
Mesenchymal-like Tumor Cells and Myofibroblastic Cancer-Associated Fibroblasts Are Associated with Progression and Immunotherapy Response of Clear Cell Renal Cell Carcinoma
- Guillaume Davidson
- Alexandra Helleux
- Yann Vano
- Veronique Lindner
- Antonin Fattori
- Marie Cerciat
- Reza T. Elaidi
- Virginie Verkarre
- Cheng-Ming Sun
- Christine Chevreau
- Mostefa Bennamoun
- Hervé Lang
- Thibault Tricard
- Wolf H. Fridman
- Catherine Sautes-Fridman
- Xiaoping Su
- Damien Plassard
- Céline Keime
- Christelle Thibault-Carpentier
- Philippe Barthelemy
- ...
Cancer Research ; Volume: 83 ; Page: 2952-2969
Article in a journal
SMARCB1 regulates a TFCP2L1-MYC transcriptional switch promoting renal medullary carcinoma transformation and ferroptosis resistance
- Bujamin Vokshi
- Guillaume Davidson
- Nassim Tawanaie Pour Sedehi
- Alexandra Helleux
- Marc Rippinger
- Alexandre Haller
- Justine Gantzer
- Jonathan Thouvenin
- Philippe Baltzinger
- Rachida Bouarich
- Valeria Manriquez
- Sakina Zaidi
- Priya Rao
- Pavlos Msaouel
- Xiaoping Su
- Hervé Lang
- Thibault Tricard
- Véronique Lindner
- Didier Surdez
- Jean-Emmanuel Kurtz
- ...
Nature Communications ; Volume: 14 ; Page: 3034
Article in a journal
An Enhancer Demethylator Phenotype Converged to Immune Dysfunction and Resistance to Immune Checkpoint Inhibitors in Clear-Cell Renal Cell Carcinomas
- Xiaofan Lu
- Yann Vano
- Alexandra Helleux
- Xiaoping Su
- Veronique Lindner
- Guillaume Davidson
- Roger Mouawad
- Jean-Philippe Spano
- Morgan Rouprêt
- Reza Elaidi
- Eva Compérat
- Virginie Verkarre
- Chengming Sun
- Christine Chevreau
- Mostefa Bennamoun
- Hervé Lang
- Thibault Tricard
- Wenxuan Cheng
- Li Xu
- Irwin Davidson
- ...
Clinical Cancer Research ; Volume: 29 ; Page: 1279-1291
Article in a journal
Racial Disparities in MiT Family Translocation Renal Cell Carcinoma
- Xiaofan Lu
- Nassim Tawanaie Pour Sedehi
- Xiaoping Su
- Fangrong Yan
- Omar Alhalabi
- Nizar Tannir
- Gabriel Malouf
Oncologist ; Volume: 28 ; Page: 1009-1013
Article in a journal
Silencing of genes by promoter hypermethylation shapes tumor microenvironment and resistance to immunotherapy in clear-cell renal cell carcinomas
- Xiaofan Lu
- Yann‐alexandre Vano
- Xiaoping Su
- Alexandra Helleux
- Véronique Lindner
- Roger Mouawad
- Jean-Philippe Spano
- Morgan Roupret
- Eva Comperat
- Virginie Verkarre
- Cheng-Ming Sun
- Mostefa Bennamoun
- Hervé Lang
- Philippe Barthélémy
- Wenxuan Cheng
- Li Xu
- Irwin Davidson
- Fangrong Yan
- Wolf Hervé Fridman
- Catherine Sautès-Fridman
- ...
Cell Reports Medicine ; Volume: 4 ; Page: 101287
2022
Article in a journal
Genetic landscape of indolent and aggressive Kaposi sarcomas
- Gabriel Malouf
- Xiaofan Lu
- Roger Mouawad
- Jean-Philippe Spano
- Philippe Grange
- F. Yan
- Selim Aractingi
- Xiaoping Su
- Nicolas Dupin
Journal of the European Academy of Dermatology and Venereology ; Volume: 36 ; Page: 2343-2351
Article in a journal
The lncRNA LENOX interacts with RAP2C to regulate metabolism and promote resistance to MAPK inhibition in melanoma.
- Giovanni Gambi
- Gabrielle Mengus
- Guillaume Davidson
- Ewout Demesmaeker
- Alessandro Cuomo
- Tiziana Bonaldi
- Vasiliki Katopodi
- Gabriel Malouf
- Eleonora Leucci
- Irwin Davidson
Cancer Research
Article in a journal
Nouvelles AMMs : pembrolizumab en adjuvant pour les carcinomes rénaux à cellules claires à haut risque de récidive après néphrectomie [New drug approval: Adjuvant Pembrolizumab in clear-cell renal-cell carcinoma at high risk for recurrence after nephrectomy]
- Maxime Brunet
- Gabriel Malouf
Bulletin du Cancer ; Volume: 109 ; Page: 875-876