Structure function of complexes involved in the HIV replication cycle, drug design

Presentation
Teams
Members
Publications

Structure function of complexes involved in the HIV replication cycle, drug design

SUBGROUP LEADER

Marc RUFF

Teams

Chromatin stability and DNA mobility
Team Leaders : Valerie LAMOUR , Marc RUFF
Department : Integrated structural biology

Members

Researchers

PhD students

Engineers

Sylvia EILER

Technicians

Sylvie DUCLAUD

Publications

2023
- The kinesin Kif21b regulates radial migration of cortical projection neurons through a non-canonical function on actin cytoskeleton
  - José Rivera Alvarez
  - Laure Asselin
  - Peggy Tilly
  - Roxane Benoit
  - Claire Batisse
  - Ludovic Richert
  - Julien Batisse
  - Bastien Morlet
  - Florian Levet
  - Noémie Schwaller
  - Yves Mély
  - Marc Ruff
  - Anne-Cécile Reymann
  - Juliette Godin
  Cell Reports ; Volume: 42 ; Page: 112744
  HAL DOI
2022
- Efficient production of protein complexes in mammalian cells using a poxvirus vector
  - Robert Drillien
  - Karine Pradeau Aubreton
  - Julien Batisse
  - Joelle Mezher
  - Emma Schenckbecher
  - Justine Marguin
  - Eric Ennifar
  - Marc Ruff
  PLoS ONE ; Volume: 17
  HAL DOI
- The HIV-1 Integrase C-Terminal domain induces TAR RNA structural changes promoting Tat binding
  - Cecilia Rocchi
  - Camille Louvat
  - Adriana Miele
  - Julien Batisse
  - Christophe Guillon
  - Lionel Ballut
  - Daniela Lener
  - Matteo Negroni
  - Marc Ruff
  - Patrice Gouet
  - Francesca Fiorini
  International Journal of Molecular Sciences ; Volume: 23 ; Page: 13742
  HAL DOI
- Efficient production of protein complexes in mammalian cells using a poxvirus vector
  - Robert Drillien
  - Karine Pradeau-Aubreton
  - Julien Batisse
  - Joëlle Mezher
  - Emma Schenckbecher
  - Justine Marguin
  - Eric Ennifar
  - Marc Ruff
  HAL DOI
2021
- The HIV-1 Integrase C-Terminal domain induces TAR RNA structural changes promoting Tat binding
  - Cecilia Rocchi
  - Camille Louvat
  - Adriana Miele
  - Julien Batisse
  - Christophe Guillon
  - Lionel Ballut
  - Daniela Lener
  - Matteo Negroni
  - Marc Ruff
  - Patrice Gouet
  - Francesca Fiorini
  HAL DOI
- Modulation of the intrinsic chromatin binding property of HIV-1 integrase by LEDGF/p75
  - Delphine Lapaillerie
  - Benoît Lelandais
  - Eric Mauro
  - Floriane Lagadec
  - Camille Tumiotto
  - Csaba Miskey
  - Guillaume Ferran
  - Natacha Kuschner
  - Christina Calmels
  - Mathieu Métifiot
  - Caroline Rooryck
  - Zoltan Ivics
  - Marc Ruff
  - Christophe Zimmer
  - Paul Lesbats
  - Jérôme Toutain
  - Vincent Parissi
  Nucleic Acids Research ; Volume: 49 ; Page: 11241-11256
  HAL DOI
2020
- NKNK: a New Essential Motif in the C-Terminal Domain of HIV-1 Group M Integrases
  - Marine Kanja
  - Pierre Cappy
  - Nicolas Levy
  - Oyindamola Oladosu
  - Sylvie Schmidt
  - Paola Rossolillo
  - Flore Winter
  - Romain Gasser
  - Christiane Moog
  - Marc Ruff
  - Matteo Negroni
  - Daniela Lener-Ory
  Journal of Virology ; Volume: 94
  HAL DOI
- Structural and Functional Studies of Human Type II Topoisomerases and their Post-Translational Modifications
  - Christophe Lotz
  - Claire Bedez
  - Claire Batisse
  - Arnaud Vanden Broeck
  - Drillien Robert
  - Marc Ruff
  - Valerie Lamour
  Biophysical Journal ; Volume: 118 ; Page: 532a
  HAL DOI
- HIV-1 Pre-Integration Complexes. Structures, Functions and Drug Design
  - Julien Batisse
  - Eduardo Bruch
  - Nicolas Lévy
  - Sylvia Eiler
  - Sylvie Duclaud
  - Patrick Schultz
  - Patrice Gouet
  - Serge Bouaziz
  - Olivier Delelis
  - Vincent Parissi
  - M. Ruff
  HAL
- HIV-1 Pre-Integration Complexes. Structures, Functions and Drug Design
  - Julien Batisse
  - Eduardo Bruch
  - Nicolas Levy
  - Sylvia Eiler
  - Sylvie Duclaud
  - Patrick Schultz
  - Patrice Gouet
  - Serge Bouaziz
  - Olivier Delelis
  - Vincent Parissi
  - Marc Ruff
  Biophysical Journal ; Volume: 118 ; Page: 500a
  HAL DOI