Chromatin stability and DNA mobility
Team Leaders : Valerie LAMOUR , Marc RUFF
Department : Integrated structural biology
Structure function of complexes involved in the HIV replication cycle, drug design
Structure function of complexes involved in the HIV replication cycle, drug design
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2017
The HIV-1 integrase-LEDGF allosteric inhibitor MUT-A: resistance profile, impairment of virus maturation and infectivity but without influence on RNA packaging or virus immunoreactivity
- Céline Amadori
- Yme Ubeles van Der Velden
- Damien Bonnard
- Igor Orlov
- Nikki van Bel
- Erwann Le Rouzic
- Laia Miralles
- Julie Brias
- Francis Chevreuil
- Daniele Spehner
- Sophie Chasset
- Benoit Ledoussal
- Luzia Mayr
- François Moreau
- Felipe García
- José Gatell
- Alessia Zamborlini
- Stéphane Emiliani
- Marc Ruff
- Bruno P. Klaholz
- ...
Retrovirology ; Volume: 14 ; Page: 50
Modulation of chromatin structure by the FACT histone chaperone complex regulates HIV-1 integration
- Julien Matysiak
- Paul Lesbats
- Eric Mauro
- Delphine Lapaillerie
- Jean-William Dupuy
- Angelica P. Lopez
- Mohamed Salah Benleulmi
- Christina Calmels
- Marie-Line Andreola
- Marc Ruff
- Manuel Llano
- Olivier Delelis
- Marc Lavigne
- Vincent Parissi
Retrovirology ; Volume: 14 ; Page: 39
Dynamics of Methylated Cytosine Flipping by UHRF1
- Christian Bronner
- Vasyl Kilin
- Krishna Gavvala
- Nicolas Barthes
- Benoît Michel
- Dongwon Shin
- Christian Boudier
- Olivier Mauffret
- Valeriy Yashchuk
- Marc Mousli
- Marc Ruff
- Florence Granger
- Sylvia Eiler
- Yitzhak Tor
- Alain Burger
- Yves Mély
Journal of the American Chemical Society ; Volume: 139 ; Page: 2520-2528
The HIV-1 Pre-Integration Complexes: Structures, Functions and Dynamics
- Nicolas Levy
- Karine Pradeau-Aubreton
- Sylvia Eiler
- Julien Batisse
- Oyindamola Oladosu
- Benoit Maillot
- Marc Ruff
Biophysical Journal ; Volume: 112 ; Page: 30a
Modulation of the functional association between the HIV-1 intasome and the nucleosome by histone amino-terminal tails
- Mohamed S Benleulmi
- Julien Matysiak
- Xavier Robert
- Csaba Miskey
- Eric Mauro
- Delphine Lapaillerie
- Paul Lesbats
- Stéphane Chaignepain
- Daniel R Henriquez
- Christina Calmels
- Oyindamola Oladosu
- Eloïse Thierry
- Oscar Leon
- Marc Lavigne
- Marie-Line Andreola
- Olivier Delelis
- Zoltán Ivics
- Marc Ruff
- Patrice Gouet
- Vincent Parissi
Retrovirology ; Volume: 14 ; Page: 54
2016
DNA minicircles clarify the specific role of DNA structure on retroviral integration
- Marc Pasi
- Damien Mornico
- Stevenn Volant
- Anna Juchet
- Julien Batisse
- Christiane Bouchier
- Vincent Parissi
- Marc Ruff
- Richard Lavery
- Marc Lavigne
Nucleic Acids Research ; Volume: 44 ; Page: 7830 - 7847
Production of unstable proteins through the formation of stable core complexes
- Nicolas Levy
- Sylvia Eiler
- Karine Pradeau-Aubreton
- Benoit Maillot
- François Stricher
- Marc Ruff
Nature Communications ; Volume: 7
2015
Intasome architecture and chromatin density modulate retroviral integration into nucleosome
- Mohamed Salah Benleulmi
- Julien Matysiak
- Daniel Rodrigo Henriquez
- Cédric Vaillant
- Paul Lesbats
- Christina Calmels
- Monica Naughtin
- Oscar Leon
- Anna Marie Skalka
- Marc Ruff
- Marc Lavigne
- Marie-Line Marie Andreola
- Vincent Parissi
Retrovirology ; Volume: 12 ; Page: 13
DNA Physical Properties and Nucleosome Positions Are Major Determinants of HIV-1 Integrase Selectivity
- Monica Naughtin
- Zofia Haftek-Terreau
- Johan Xavier
- Sam Meyer
- Maud Silvain
- Yan Jaszczyszyn
- Nicolas Lévy
- Vincent Miele
- Mohamed Salah Benleulmi
- Marc Ruff
- Vincent Parissi
- Cédric Vaillant
- Marc Lavigne
PLoS ONE ; Volume: 10 ; Page: e0129427
2014
Functional relationship between matrix metalloproteinase‐11 and matrix metalloproteinase‐14
- Emilie Buache
- Robert Thai
- Corinne Wendling
- Fabien Alpy
- Adeline Page
- Marie‐pierre Chenard
- Vincent Dive
- Marc Ruff
- Annick Dejaegere
- Catherine Tomasetto
- Marie‐christine Rio
Cancer Medicine ; Volume: 3 ; Page: 1197-1210