Structure function of complexes involved in the HIV replication cycle, drug design

Publications

• 2016

  • DNA minicircles clarify the specific role of DNA structure on retroviral integration

    • Marc Pasi
    • Damien Mornico
    • Stevenn Volant
    • Anna Juchet
    • Julien Batisse
    • Christiane Bouchier
    • Vincent Parissi
    • Marc Ruff
    • Richard Lavery
    • Marc Lavigne

    Nucleic Acids Research ; Volume: 44 ; Page: 7830 - 7847

    HAL DOI

  • Production of unstable proteins through the formation of stable core complexes

    • Nicolas Levy
    • Sylvia Eiler
    • Karine Pradeau-Aubreton
    • Benoit Maillot
    • François Stricher
    • Marc Ruff

    Nature Communications ; Volume: 7

    HAL DOI

• 2015

  • Site-Selective Monitoring of the Interaction of the SRA Domain of UHRF1 with Target DNA Sequences Labeled with 2-Aminopurine

    • Vanille Greiner
    • Lesia Kovalenko
    • Nicolas Humbert
    • Ludovic Richert
    • Catherine Birck
    • Marc Ruff
    • Olga A. Zaporozhets
    • Sirano Dhe-Paganon
    • Christian Bronner
    • Yves Mély

    Biochemistry ; Volume: 54 ; Page: 6012-6020

    HAL DOI

  • Clinical massively parallel sequencing for the diagnosis of myopathies

    • Svetlana Gorokhova
    • Valerie Biancalana
    • Nicolas Lévy
    • Jocelyn Laporte
    • Marc Bartoli
    • Martin Krahn

    Revue Neurologique ; Volume: 171 ; Page: 558-571

    HAL DOI

  • Intasome architecture and chromatin density modulate retroviral integration into nucleosome

    • Mohamed Salah Benleulmi
    • Julien Matysiak
    • Daniel Rodrigo Henriquez
    • Cédric Vaillant
    • Paul Lesbats
    • Christina Calmels
    • Monica Naughtin
    • Oscar Leon
    • Anna Marie Skalka
    • Marc Ruff
    • Marc Lavigne
    • Marie-Line Marie Andreola
    • Vincent Parissi

    Retrovirology ; Volume: 12 ; Page: 13

    HAL DOI

  • DNA Physical Properties and Nucleosome Positions Are Major Determinants of HIV-1 Integrase Selectivity

    • Monica Naughtin
    • Zofia Haftek-Terreau
    • Johan Xavier
    • Sam Meyer
    • Maud Silvain
    • Yan Jaszczyszyn
    • Nicolas Lévy
    • Vincent Miele
    • Mohamed Salah Benleulmi
    • Marc Ruff
    • Vincent Parissi
    • Cédric Vaillant
    • Marc Lavigne

    PLoS ONE ; Volume: 10 ; Page: e0129427

    HAL DOI

• 2014

  • HSPA8/HSC70 chaperone protein

    • François Stricher
    • Christophe Macri
    • M. Ruff
    • Sylviane Muller

    Autophagy ; Volume: 9 ; Page: 1937-1954

    HAL DOI

  • Functional relationship between matrix metalloproteinase‐11 and matrix metalloproteinase‐14

    • Emilie Buache
    • Robert Thai
    • Corinne Wendling
    • Fabien Alpy
    • Adeline Page
    • Marie‐pierre Chenard
    • Vincent Dive
    • Marc Ruff
    • Annick Dejaegere
    • Catherine Tomasetto
    • Marie‐christine Rio

    Cancer Medicine ; Volume: 3 ; Page: 1197-1210

    HAL DOI

• 2013

  • Dual inhibition of HIV-1 replication by integrase-LEDGF allosteric inhibitors is predominant at the post-integration stage.

    • Erwann Le Rouzic
    • Damien Bonnard
    • Sophie Chasset
    • Jean-Michel Bruneau
    • Francis Chevreuil
    • Frédéric Le Strat
    • Juliette Nguyen
    • Roxane Beauvoir
    • Céline Amadori
    • Julie Brias
    • Sophie Vomscheid
    • Sylvia Eiler
    • Nicolas Lévy
    • Olivier Delelis
    • Eric Deprez
    • Ali Saïb
    • Alessia Zamborlini
    • Stéphane Emiliani
    • Marc Ruff
    • Benoit Ledoussal
    • ...

    Retrovirology ; Volume: 10 ; Page: 144

    HAL DOI

  • Structural and functional studies of the HIV-1 pre-integration complex

    • Nicolas Lévy
    • Sylvia Eiler
    • Karine Pradeau-Aubreton
    • Corinne Crucifix
    • Aurélie Schaetzel
    • Robert Drillien
    • Vincent Parissi
    • Stéphane Emiliani
    • Yves Mely
    • Patrick Schultz
    • Marc Ruff

    Retrovirology ; Volume: 10 ; Page: P76

    HAL