Chromatin stability and DNA mobility
Team Leaders : Valerie LAMOUR , Marc RUFF
Department : Integrated structural biology
Structure function of complexes involved in the HIV replication cycle, drug design
Structure function of complexes involved in the HIV replication cycle, drug design
SUBGROUP LEADER
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Publications
2013
Dual inhibition of HIV-1 replication by integrase-LEDGF allosteric inhibitors is predominant at the post-integration stage.
- Erwann Le Rouzic
- Damien Bonnard
- Sophie Chasset
- Jean-Michel Bruneau
- Francis Chevreuil
- Frédéric Le Strat
- Juliette Nguyen
- Roxane Beauvoir
- Céline Amadori
- Julie Brias
- Sophie Vomscheid
- Sylvia Eiler
- Nicolas Lévy
- Olivier Delelis
- Eric Deprez
- Ali Saïb
- Alessia Zamborlini
- Stéphane Emiliani
- Marc Ruff
- Benoit Ledoussal
- ...
Retrovirology ; Volume: 10 ; Page: 144
Structural and functional studies of the HIV-1 pre-integration complex
- Nicolas Lévy
- Sylvia Eiler
- Karine Pradeau-Aubreton
- Corinne Crucifix
- Aurélie Schaetzel
- Robert Drillien
- Vincent Parissi
- Stéphane Emiliani
- Yves Mely
- Patrick Schultz
- Marc Ruff
Retrovirology ; Volume: 10 ; Page: P76
2012
Structural and functional role of INI1 and LEDGF in the HIV-1 preintegration complex.
- Benoit Maillot
- Nicolas Lévy
- Sylvia Eiler
- Corinne Crucifix
- Florence Granger
- Ludovic Richert
- Pascal Didier
- Julien Godet
- Karine Pradeau-Aubreton
- Stéphane Emiliani
- Alexis Nazabal
- Paul Lesbats
- Vincent Parissi
- Yves Mely
- Dino Moras
- Patrick Schultz
- Marc Ruff
PLoS ONE ; Volume: 8 ; Page: e60734
Expression of functional full-length hSRC-1 in eukaryotic cells using modified vaccinia virus Ankara and baculovirus
- Judit Osz
- Karine Pradeau-Aubreton
- Robert Drillien
- Nathalie Troffer-Charlier
- Isabelle Kolb-Cheynel
- Arnaud Poterszman
- Marc Ruff
- Dino Moras
- Natacha Rochel
Analytical Biochemistry ; Volume: 426 ; Page: 106-108
2011
Mutations affecting interaction of integrase with TNPO3 do not prevent HIV-1 cDNA nuclear import.
- Alexandra Cribier
- Emmanuel Ségéral
- Olivier Delelis
- Vincent Parissi
- Aurélie Simon
- Marc Ruff
- Richard Benarous
- Stéphane Emiliani
Retrovirology ; Volume: 8 ; Page: 104
Using Vaccinia's innate ability to introduce DNA into mammalian cells for production of recombinant proteins
- B Jester
- Robert Drillien
- Marc Ruff
- Catherine Florentz
Journal of biotechnology ; Volume: 156 ; Page: 211-213
2010
Vectors for recombinational cloning and gene expression in mammalian cells using modified vaccinia virus Ankara
- Karine Pradeau Aubreton
- Marc Ruff
- Jean-Marie Garnier
- Patrick Schultz
- Robert Drillien
Analytical Biochemistry ; Volume: 404 ; Page: 103-105
2009
Towards high-throughput identification of endocrine disrupting compounds with mass spectrometry.
- Cédric Bovet
- Benoit Plet
- Marc Ruff
- Sylvia Eiler
- Florence Granger
- Andreas Panagiotidis
- Ryan Wenzel
- Alexis Nazabal
- Dino Moras
- Renato Zenobi
Toxicology in Vitro ; Volume: 23 ; Page: 704-9
Structural basis for HIV-1 DNA integration in the human genome, role of the LEDGF/P75 cofactor.
- Fabrice Michel
- Corinne Crucifix
- Florence Granger
- Sylvia Eiler
- Jean-François Mouscadet
- Sergei Korolev
- Julia Agapkina
- Rustam Ziganshin
- Marina Gottikh
- Alexis Nazabal
- Stéphane Emiliani
- Richard Benarous
- Dino Moras
- Patrick Schultz
- Marc Ruff
EMBO Journal ; Volume: 28 ; Page: 980-91
Structural basis for HIV-1 DNA integration in the human genome
- Fabrice Michel
- Sylvia Eiler
- Florence Granger
- Jean-François Mouscadet
- Marina Gottikh
- Alexis Nazabal
- Stéphane Emiliani
- Richard Benarous
- Dino Moras
- Patrick Schultz
- Marc Ruff
Retrovirology ; Frontiers of Retrovirology: Complex retroviruses, retroelements and their hosts ; Volume: 6 ; Page: P79