
Cell physics
Cell physics
The Cell Physics team characterizes self-organization of cells, cell motion, cell division, morphogenesis of tissues in vitro and in vivo. The projects involve synergized approaches between theoretical physics, cell biology, microfabrication.
For more details, see : riveline.igbmc.science
Members
Researchers
PhD students
Engineers
Current projects
Self-organisation in living matter : from cell motility and cytokinesis to morphogenesis
- Cell motility: Ratchetaxis and Scallop Theorem
Publications.
How a cell moves from a point A to a point B in the absence of long range gradient.
- Lammelipodia growth promoter: supramolecular compounds specific to actin
Publications.
Synthetic polyamines trigger growth of lamellipodia within minutes (scale bar 20μm).
- Cytokinesis: myosin clusters dynamics and rings constriction across systems
Publications.
Myosin clusters dynamics determine the evolutions of cytokinetic rings visualized in a single focal plane with micro-fabricated cavities (myosin, scale bar 5μm).
- Morphogenesis in vitro: collective effects in cells
Publications.
Elongation of an epithelial colony results from nematic fields and topological defects (scale bar 50μm).
- Scaling and injections of fission yeast
Publications.
Asymmetric division : Scaling arguments predict the localisation of septum correlated with differences in cell ends (left).
Fission yeast behaves as a balloon and can be injected (right, scale bar 5μm).
- Reinforcement of focal contacts and cell-cell junctions (adherens junctions and hemidesmosomes)
Publications.
Adhesive contacts elongate with local forces within minutes (compare top and bottom, scale bar 5μm).
They recruit adhesion proteins while keeping their matter density constant.
For more details see : riveline.igbmc.science
Collaborations and networks
- HFSP coordinator 2018 with Alf Honigmann (MPI-CBG Dresden), Anne Grapin-Botton (Danstem, Copenhagen), Masaki Sano (University of Tokyo)
- SNF 2019 with Olivier Pertz (University of Bern), Damian Brunner (University of Zurich), Karsten Kruse (University of Geneva)
Funding and partners
- HFSP coordinator 2018 with Alf Honigmann (MPI-CBG Dresden), Anne Grapin-Botton (Danstem, Copenhagen), Masaki Sano (University of Tokyo)
- SNF 2019 with Olivier Pertz (University of Bern), Damian Brunner (University of Zurich), Karsten Kruse (University of Geneva)
Job offers
News

A dashboard to study cell movement
Individual cells move in vivo in complex 3D environments. Their motion occurs at zero force and requires symmetry breaking. In this study at the…
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Awards and recognitions
- HFSP coordinator 2018
- Fellowship Simone et Cino del Duca 2011
- ATIP CNRS 2010
Resources
See the website for the Cell Physics Master at the University of Strasbourg
Publications
2022
Interplay between cell height variations and planar pulsations in epithelial monolayers
- Raghavan Thiagarajan
- Mandar Inamdar
- Daniel Riveline
European Physical Journal E: Soft matter and biological physics ; Volume: 45 ; Page: 49
Interplay between cell height variations and planar pulsations in epithelial monolayers
- Raghavan Thiagarajan
- Mandar M Inamdar
- Daniel Riveline
European Physical Journal E: Soft matter and biological physics ; Volume: 45 ; Page: 49
2021
Spontaneous rotations in epithelia as an interplay between cell polarity and RhoA activity at boundaries.
- Simon Lo Vecchio
- Olivier Pertz
- Marcela Szopos
- Laurent Navoret
- Daniel Riveline
Pulsations and flows in tissues: two collective dynamics with simple cellular rules
- Raghavan Thiagarajan
- Alka Bhat
- Guillaume Salbreux
- Mandar Inamdar
- Daniel Riveline
Temporal correlation between oscillating force dipoles drives 3D single cell migration
- A. Godeau
- M. Leoni
- J. Comelles
- H. Delanoë-Ayari
- A. Ott
- S. Harlepp
- P. Sens
- Daniel Riveline
Epithelial colonies in vitro elongate through collective effects
- Jordi Comelles
- Soumya Ss
- Linjie Lu
- Emilie Le Maout
- S Anvitha
- Guillaume Salbreux
- Frank Jülicher
- Mandar Inamdar
- Daniel Riveline
eLife ; Volume: 10
2020
Control and mechanisms of pulsatile flows in epithelial monolayers
- Raghavan Thiagarajan
- Alka Bhat
- Guillaume Salbreux
- Mandar Inamdar
- Daniel Riveline
Temporal correlation between oscillating force dipoles drives 3D single cell migration
- A. Godeau
- M. Leoni
- J. Comelles
- H. Delanoë-Ayari
- A. Ott
- S. Harlepp
- P. Sens
- Daniel Riveline
Ratchetaxis in Channels: Entry Point and Local Asymmetry Set Cell Directions in Confinement
- Emilie Le Maout
- Simon Lo Vecchio
- Praveen Kumar Korla
- Jim Jinn-Chyuan Sheu
- Daniel Riveline
Biophysical Journal ; Volume: 119 ; Page: 1301-1308
Cell motion as a stochastic process controlled by focal contacts dynamics
- Simon Lo Vecchio
- Raghavan Thiagarajan
- David Caballero
- Vincent Vigon
- Laurent Navoret
- Raphael Voituriez
- Daniel Riveline
Cell Systems ; Volume: 10 ; Page: 535-542.e4