
Cell physics
Cell physics
The Cell Physics team characterizes self-organization of cells, cell motion, cell division, morphogenesis of tissues in vitro and in vivo. The projects involve synergized approaches between theoretical physics, cell biology, microfabrication.
For more details, see : riveline.igbmc.science
Members
Researchers
PhD students
Current projects
Self-organisation in living matter : from cell motility and cytokinesis to morphogenesis
- Cell motility: Ratchetaxis and Scallop Theorem
Publications.
How a cell moves from a point A to a point B in the absence of long range gradient.
- Lammelipodia growth promoter: supramolecular compounds specific to actin
Publications.
Synthetic polyamines trigger growth of lamellipodia within minutes (scale bar 20μm).
- Cytokinesis: myosin clusters dynamics and rings constriction across systems
Publications.
Myosin clusters dynamics determine the evolutions of cytokinetic rings visualized in a single focal plane with micro-fabricated cavities (myosin, scale bar 5μm).
- Morphogenesis in vitro: collective effects in cells
Publications.
Elongation of an epithelial colony results from nematic fields and topological defects (scale bar 50μm).
- Scaling and injections of fission yeast
Publications.
Asymmetric division : Scaling arguments predict the localisation of septum correlated with differences in cell ends (left).
Fission yeast behaves as a balloon and can be injected (right, scale bar 5μm).
- Reinforcement of focal contacts and cell-cell junctions (adherens junctions and hemidesmosomes)
Publications.
Adhesive contacts elongate with local forces within minutes (compare top and bottom, scale bar 5μm).
They recruit adhesion proteins while keeping their matter density constant.
For more details see : riveline.igbmc.science
Collaborations and networks
- HFSP coordinator 2018 with Alf Honigmann (MPI-CBG Dresden), Anne Grapin-Botton (Danstem, Copenhagen), Masaki Sano (University of Tokyo)
- SNF 2019 with Olivier Pertz (University of Bern), Damian Brunner (University of Zurich), Karsten Kruse (University of Geneva)
Funding and partners
- HFSP coordinator 2018 with Alf Honigmann (MPI-CBG Dresden), Anne Grapin-Botton (Danstem, Copenhagen), Masaki Sano (University of Tokyo)
- SNF 2019 with Olivier Pertz (University of Bern), Damian Brunner (University of Zurich), Karsten Kruse (University of Geneva)
News

A dashboard to study cell movement
Individual cells move in vivo in complex 3D environments. Their motion occurs at zero force and requires symmetry breaking. In this study at the…
Read more
Awards and recognitions
- HFSP coordinator 2018
- Fellowship Simone et Cino del Duca 2011
- ATIP CNRS 2010
Resources
See the website for the Cell Physics Master at the University of Strasbourg
Publications
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2020
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How to orient cells in microcavities for high resolution imaging of cytokinesis and lumen formation
- Alka Bhat
- Linjie Lu
- Chen-Ho Wang
- Simon Lo Vecchio
- Riccardo Maraspini
- Alf Honigmann
- Daniel Riveline
Methods in Cell Biology ; Page: 25-41
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Ratchetaxis in Channels: Entry Point and Local Asymmetry Set Cell Directions in Confinement
- Emilie Le Maout
- Simon Lo Vecchio
- Praveen Kumar Korla
- Jim Jinn-Chyuan Sheu
- Daniel Riveline
Biophysical Journal ; Volume: 119 ; Page: 1301-1308
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Generation of fluorescent cell-derived-matrix to study 3D cell migration
- Amélie Luise Godeau
- Hélène Delanoë-Ayari
- Daniel Riveline
Methods in Cell Biology ; Page: 185-203
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2019
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Ends and middle: global force balance determines septum location in fission yeast
- Xavier Le Goff
- Jordi Comelles
- Charles Kervrann
- Daniel Riveline
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2018
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Active bundles of polar and bipolar filaments
- F. Kreten
- Ch. Hoffmann
- Daniel Riveline
- K. Kruse
Physical Review E ; Volume: 98
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The Science of Living Matter for Tomorrow
- G. Bauer
- N. Fakhri
- A. Kicheva
- J. Kondev
- K. Kruse
- H. Noji
- Daniel Riveline
- T.E. Saunders
- M. Thattai
- E. Wieschaus
Cell Systems ; Volume: 6 ; Page: 400-402
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Spatial Fluctuations at Vertices of Epithelial Layers: Quantification of Regulation by Rho Pathway
- Etienne Fodor
- Vishwajeet Mehandia
- Jordi Comelles
- Raghavan Thiagarajan
- Nir Gov
- Paolo Visco
- Frédéric van Wijland
- Daniel Riveline
Biophysical Journal ; Volume: 114 ; Page: 939-946
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Directing cell migration on flat substrates and in confinement with microfabrication and microfluidics
- Emilie Le Maout
- Simon Lo Vecchio
- Alka Bhat
- Daniel Riveline
Microfluidics in Cell Biology Part B: Microfluidics in Single Cells ; Page: 109-132
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2017
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The Forms of Tissues, or Cell-aggregates': D'Arcy Thompson's influence and its limits
- François Graner
- Daniel Riveline
Development: For advances in developmental biology and stem cells ; Volume: 144 ; Page: 4226-4237
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Interface between Physics and Biology: Training a New Generation of Creative Bilingual Scientists
- Daniel Riveline
- Karsten Kruse
Trends in Cell Biology ; Volume: 27 ; Page: 541-543
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